For 2016 onwards, Lowes signed a three-year contract backed by Aprilia, enabling him to continue in Moto2 for 2016 with the Gresini team and a change from Speed Up to Kalex chassis. As well as this, Lowes has the added benefit of being Aprilia's official MotoGP test rider, with an anticipated move to compete for Aprilia in the premier MotoGP class for the 2017 and 2018 seasons.